Characterization of virus produced by a lymphoma induced by inoculation of AKR MCF-247 virus.

نویسندگان

  • F S Pedersen
  • D L Buchhagen
  • C Y Chen
  • E F Hays
  • W A Haseltine
چکیده

We report the characterization of the virus produced by a lymphoid cell line derived from a lymphoma of an AKR mouse after injection of the polytropic AKR virus MCF-247. The virus displays polytropic host range properties and is indistinguishable from MCF-247 as judged by analysis of the large RNase T1-resistant oligonucleotides of the RNA genome. Restriction enzyme analysis of cellular DNA revealed the presence of sequences homologous to MCF-247 genomic RNA. The EcoRI cleavage fragments were characteristic of MCF-247 DNA provirus cleavage products.

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عنوان ژورنال:
  • Journal of virology

دوره 35 1  شماره 

صفحات  -

تاریخ انتشار 1980